SLU-PP-332
Product details
SLU-PP-332 is a synthetic pan-agonist of estrogen-related receptors (ERRα, ERRβ, ERRγ). Despite the name, ERRs are orphan nuclear receptors not regulated by estrogen; they function as transcription factors for genes involved in mitochondrial biogenesis and oxidative phosphorylation.
Research Applications: - ERRα/β/γ binding affinity and selectivity characterization - Orphan nuclear receptor transcriptional activation assays - PGC-1α coactivator recruitment studies - Mitochondrial biogenesis gene expression profiling - Oxidative phosphorylation pathway analysis - ERR target gene (OXPHOS, TCA cycle) reporter assays
Molecular Information: - Target: ERRα (EC50: 98 nM), ERRβ (EC50: 230 nM), ERRγ (EC50: 430 nM) - Mechanism: Pan-ERR agonist - Purity: >99% (HPLC verified)
Form: Lyophilized powder Storage: Store at -20°C. Protect from light.